Category Archives: Personalized Therapies
Participants of pioneering CRISPR gene editing trial see vision improve
In early 2020, surgeons at the OHSU Casey Eye Institute performed the first in-body CRISPR gene editing procedure as part of the Phase 1/2 BRILLIANCE clinical trial. Now, new trial […]
Doctor remains “cancer-free” a year after world-first treatment
GBM cells (credit: Brain Tumour Research Centre of Excellence at Queen Mary Univerity of London) https://braintumourresearch.org/en-us/blogs/latest-news/doctor-remains-cancer-free-a-year-after-world-first-treatment
John Hancock and MIT AgeLab launch longevity collaboration
Five-year, multimillion dollar collaboration will develop cutting-edge longevity preparedness index to drive better health and wealth outcomes. https://longevity.technology/news/john-hancock-and-mit-agelab-launch-longevity-collaboration/
New study reveals the key role of mitochondrial proteins in cardiac regeneration
From left to right: Immunofluorescence image of a section of a cryoinjured zebrafish heart, showing proliferating cells (white), cardiomyocytes (red), and cell nuclei (blue); Electron microscopy image of mitochondria; Blue […]
How aging clocks tick
https://portal.uni-koeln.de/en/universitaet/aktuell/press-releases/single-news/how-aging-clocks-tick
Is Liz Parrish the world’s most genetically modified person? Why it might not be such a good thing
Is Liz Parrish the world’s most GM person? Maybe. What are the risks for her and the community? https://ipscell.com/2024/05/is-liz-parrish-the-worlds-most-genetically-modified-person/
Hacking the immune system could slow ageing — here’s how
Researchers think that the immune system could be the key to healthy ageing. Credit: Ami Vitale/Panos Pictures https://www.nature.com/articles/d41586-024-01274-3
Researchers Discover “Training Program” That Turns Stomach Stem Cells Into Acid-Producers
Credit: Julien Tromeur/ Pixabay https://www.technologynetworks.com/cell-science/news/researchers-discover-training-program-that-turns-stomach-stem-cells-into-acid-producers-386677
First patient to get gene-edited pig kidney transplant dies
Surgeons perform the world’s first genetically modified pig kidney transplant into a living human at Massachusetts General Hospital, in Boston, March 16, 2024. (Massachusetts General Hospital via AP) https://www.voanews.com/a/first-patient-to-get-gene-edited-pig-kidney-transplant-dies-/7607872.html
Regeneron’s Gene Therapy Shows ‘Dramatic’ Hearing Improvement in Deaf Kids
Pictured: Regeneron logo on a light brown building/Shutterstock/Lev Radin https://www.biospace.com/article/asgct24-regeneron-s-gene-therapy-shows-dramatic-hearing-improvement-in-deaf-kids/
Fulfilling the promise of cell & gene therapies through manufacturing (Part I)
The Top Line (Questex) https://www.fiercepharma.com/manufacturing/fulfilling-promise-cell-gene-therapies-through-manufacturing-part-i
World’s 1st ‘tooth regrowth medicine’ to be tested in Japan from Sept. 2024
A tooth that grew in a mouse with a congenital tooth deficiency, is seen growing after it was given the medicine, in this photo provided by Kitano Hospital. https://mainichi.jp/english/articles/20240503/p2a/00m/0sc/012000c
Incredible medicine that regrows teeth is about to enter human trials
Image: puhhha / Adobe https://bgr.com/science/incredible-medicine-that-regrows-teeth-is-about-to-enter-human-trials/
Amazingly Detailed Images Reveal a Single Cubic Millimeter of Human Brain in 3D
A rendering of the excitatory neurons in a section of the sample. (Google Research & Lichtman Lab/Harvard University. Renderings by D. Berger/Harvard University) https://www.sciencealert.com/amazingly-detailed-images-reveal-a-single-cubic-millimeter-of-human-brain-in-3d
Met investigates ‘stem-cell autism cure’ claim
The Royal Borough of Greenwich says it is aware of concerns surrounding “experimental procedures” on autistic children https://www.bbc.co.uk/news/uk-england-london-68759263.amp
Stem Cell Therapy Boosts Natural Repair After Cardiac Arrest
[Figure 1. Schematic of novel stem cell therapy with metabolic glycoengineering (MGE) for brain repair after cardiac arrest (CA). Conditions were characterized and optimized in vitro to modify human neural […]
59-year-old Man Who Had Type 2 Diabetes for 25 Years is Cured by Stem Cells
Regular insulin and a syringe from ampoules and vials of medicines https://www.goodnewsnetwork.org/59-year-old-man-who-had-type-2-diabetes-for-25-years-is-cured-by-stem-cells/
Revolutionizing Lupus Care: How Stem Cell Innovations Are Changing Lives?
Unveiling Lupus: Why is it a Big Deal? Can Stem Cell Treatment Make a Difference? Explains Dr Aravind Badiger, Technical Director of BDR Pharmaceuticals. https://www.thehealthsite.com/photo-gallery/revolutionizing-lupus-care-how-stem-cell-innovations-are-changing-lives-1090607/amp/#
University Hospitals first in Northeast Ohio to offer outpatient stem cell therapies
Signal of Benefit for Stem Cell Therapy in Progressive MS
3 Colorado patients infected from stem-cell treatments in Mexico
Microautophagy is essential for preventing aging
Researchers from Osaka University have shown for the first time that damaged lysosomes are repaired by a process called microautophagy, which is essential for preventing aging. https://resou.osaka-u.ac.jp/en/research/2023/20231121_1
Your Body’s Cells Could Age Years in a Single Day, Challenging Past Research
(Klaus Vedfelt/Getty Images) https://www.sciencealert.com/your-bodys-cells-could-age-years-in-a-single-day-challenging-past-research
New Research Links Popular Hormone Drugs to Brain Tumors
A recent study indicates a significant increase in the risk of developing intracranial meningioma associated with prolonged use of certain progestogens, hormones commonly used in women’s health. This first-of-its-kind study, […]
Study challenges one-size-fits-all approach to vitamin D supplementation guidelines
A Common Sleeping Pill May Reduce Build-Up of Alzheimer’s Proteins, Study Finds
(Tero Vesalainen/iStock/Getty Images) https://www.sciencealert.com/a-common-sleeping-pill-may-reduce-build-up-of-alzheimers-proteins-study-finds
EPA, FDA, and USDA Issue Joint Regulatory Plan for Biotechnology
Stem Cell Therapy Improves Post-Stroke Motor Function
Gene-therapy breakthrough allows congenitally deaf children to hear
Zheng-Yi Chen of Massachusetts Eye and Ear Infirmary and Harvard Medical School co-led the team that developed the gene therapy. https://www.news.harvard.edu/gazette/story/2024/01/gene-therapy-breakthrough-allows-congenitally-deaf-children-to-hear/
BioRestorative Therapies propelling cell-based therapies for lower back pain, Obesity, Type 2 diabetes and more
Researchers identify genetic factors that help some reach 100 years with sharp minds
(Photo credit: Adobe Stock) https://www.psypost.org/researchers-identify-genetic-factors-that-help-some-reach-100-years-with-sharp-minds/#google_vignette
Brain plasticity, not just neurons
An international team of researchers from USA, Italy, and Germany demonstrates a new mechanism of neural plasticity underlying learning and memory processes. https://pressroom.unitn.it/comunicato-stampa/brain-plasticity-not-just-neurons
UMSOM Preclinical Study Finds Novel Stem Cell Therapy Boosts Neural Repair After Cardiac Arrest
New stem cell therapy in animal model could eventually lead to viable treatment option https://www.medschool.umaryland.edu/news/2024/umsom-preclinical-study-finds-novel-stem-cell-therapy-boosts-neural-repair-after-cardiac-arrest-.html
Brain-cell transplants are the newest experimental epilepsy treatment
SCG and A*STAR to develop better stem cell manufacturing
ISTOCK/DAVIZRO https://www.bioprocessintl.com/deal-making/scg-and-a-star-to-develop-better-stem-cell-manufacturing
Researchers identify new genetic form of Alzheimer’s that is present in millions of people
A researcher handles a brain sample. INMA FLORES https://english.elpais.com/science-tech/2024-05-06/researchers-identify-new-genetic-form-of-alzheimers-that-is-present-in-millions-of-people.html?outputType=amp
Canadian grandad flies to Sheffield to meet lifesaving stem cell donor
Tom Marshall (left) said it was an honour to donate to Mr Neander (right) https://www.bbc.com/news/uk-england-south-yorkshire-68961347.amp
Scientists are trying to get cows pregnant with synthetic embryos
STEPHANIE ARNETT/MITTR https://www.technologyreview.com/2024/05/06/1092055/scientists-are-trying-to-get-cows-pregnant-with-synthetic-embryos/amp/
Uncovering the secret of long-lived stem cells
The levels of cyclophilin A, shown here in red, decline as hematopoietic stem cells age. Image courtesy of the authors/Nature Cell Biology, 2024. https://blogs.bcm.edu/2024/04/30/from-the-labs-uncovering-the-secret-of-long-lived-stem-cells/